The British Transplant Games are organised on behalf of the Transplant Sport UK (TSUK). The Games were inaugurated in 1978 in Portsmouth by Maurice Slapak, who at the time was a Consultant Transplant Surgeon. Approximately 100 participants took part in the first Games in a one day event. Over the past 30 years, the British Transplant Games has grown to a four day annual event for over 600 competitors and nearly 1000 supporters.

The Games have been staged annually since 1978 in 15 host cities including Portsmouth, Newcastle, Cardiff, Birmingham, Exeter, Liverpool, Belfast, Edinburgh, Glasgow, Leeds, Leicester, London, Manchester, Sheffield and Norwich, Loughborough and Bath.